THE ROLE OF PHYSICAL ACTIVITY IN THE PROGRESSION OF CHRONIC END-STAGE RENAL FAILURE

Adem Hykolli¹, Adriatik Jahjaga¹, Lutfi Zylbeari^{2, *}, Arben Krasniqi³, Bajram Shyti⁴

¹Faculty of Medicine, University of Prishtina ,,Hasan Prishtina”, Prishtina, Kosovo - ²Physical Medicine and Rehabilitation Clinic, University Clinical Center of Kosovo, Republic of Kosovo - ³University of Tetova, Faculty of Medical Sciences, Tetova, R.N. Macedonia - ⁴Physical Medicine and Rehabilitation Clinic, University Clinical Center of Kosovo, Republic of Kosovo

Objective: Chronic kidney failure in the final stage. There are verified facts that moderate physical activity, physical exercises, walking, swimming, aerobics have a positive effect in slowing down the rapid progression of the disease in patients with diabetes and high blood pressure. Previous studies have shown that physical activities with moderate intensity can significantly affect the slowing down of the progress of chronic kidney failure (CKF). it has been verified that physical inactivity, sedentarily, adiposity in patients with end-stage chronic failure affects the acceleration and rapid progress of chronic renal failure. Future studies are necessary to better clarify the benefits of different levels of intensity with kidney function.

Purpose of the work: The purpose of this study was to verify the influence of moderate physical activity in slowing down the rapid progression of CKD (Chronic Terminal Renal Insufficiency) affecting the balance of diabetes, uremic dyslipidemia, microalbuminuria, proteinuria and arterial hypertension (HTA).

Material and methods of the study: The study was "cross-sectional". The degree of renal damage, namely the glomerular filtration rate (GFR) was assessed according to the Cockcroft & Gault formula. Physical activity was assessed using the rate of glomerular filtration rate correlated with HTA, lipid profile, mycoalbumin-nurine. and proteinurin. The number of patients with CRFT was 80 (35 women + 45 men) with an identical average age of 58.70±6.00 years and GFR 60-89 mL/min. The patients were randomized according to physical activity into two groups (40 patients who had moderate physical activity had it within 5-6 days a week of 25-30 minutes, while 40 of the patients had no physical activity and had a sedentary life.

Results obtained: In general, patients who during the study had developed physical activity (light and moderate) did not have a significant decrease in GFR compared to patients who had not had physical activity who had a decrease in GFR of 18-25 %.

Conclusion: At the end of our study, we can conclude that physical activity, walking, swimming, yoga, cycling significantly has positive effects on the progression of renal damage. Therefore, appeal to increase the awareness of all patients with CRF and those with ESRD to engage in moderate physical activity (from 25-30 minutes only 5 days a week, respecting the hypoproteinemic diet, reducing the use of salt, to slowed down the rapid progression of renal failure. In general, patients with (moderate) physical activity who had developed physical activity during the study did not manifest a significant decrease in glomerular filtration rate compared to patients who had not had physical activity and showed a decrease in glomerular filtration rate of 18-25%.