IS DEL NIDO CARDIOPLEGIA A SAFE HAVEN FOR ADULT ISOLATED CORONARY BYPASS SURGERY? THE EFFECT OF DEL NIDO CARDIOPLEGIA ON MYOCARDIAL PROTECTION AND ARRHYTHMIA

Cem Atik

Osmaniye Private New Life Hospital, Cardiovascular Surgery Unit, Osmaniye, Turkey

Background: In this study, it was aimed to compare the intraoperative and postoperative results of the use of conventional blood cardioplegia and del nido cardioplegia solution in terms of myocardial protection and the formation of arrhythmias.

Materials and methods: The study was planned as a retrospective case-control study. The study population consisted of all patients who underwent isolated coronary artery bypass graft surgery (CABG) performed by a single team at a private hospital in Osmaniye between March 2016 and May 2020. Power analysis was performed to determine the adequacy of sample size.

Results: The groups had similar sociodemographic and clinical characteristics The DNC group had significantly lower cross-clamp time, pump time, amount of cardioplegia, use of inotropic agents, and need for defibrillation than the BC group during CABG The DNC group had significantly lower rates of hospitalization, right ventricular dysfunction, atrial fibrillation, ventricular arrhythmia, and mortality rates than the BC group.

Conclusion: These results indicate that the DNC is an easy-to-use procedure for CABG patients because it provides short ischemic and cardioplegia time and less oxidative stress and hyperkalemic arrest.