EFFECTS OF OMEPRAZOLE TEST AND COMPREHENSIVE NURSING INTERVENTION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH GASTROESOPHAGEAL REFLUX DISEASE

Min Shi¹, Mingming Shui^{2, *}

¹Department of Gastrointestinal Surgery, Wuhan First People's Hospital, Wuhan 430000, Hubei, China - ²Department of Imaging, Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi 445000, Hubei, China

Introduction: chronic obstructive pulmona-ry disease (COPD) is a common and frequently-occurring respiratory disease. This work aimed to explore the effects of omeprazole and comprehensive nursing intervention on chronic obstructive pulmonary disease (COPD) with gastroesophageal reflux disease (GERD). 

Material and method: a total of 150 COPD patients were divided into three groups (groups A, B, and C with 50 cases in each group) for analysis the diagnostic effects omeprazole. Meanwhile, 50 COPD patients with GERD were divided into two groups (groups D and E with 25 cases in each group) for exploring the effects of comprehenaive nursing intervention. The symptom score, symptom frequency grade, decline rate, diagnostic sensitivity, specificity, coincidence rate, psychological state (self-rating anxiety scale (SAS) and self-rating depression scale (SDS)), and nursing satisfaction were observed and compared. 

Result: the results showed that the reflux symptom scores decreased by (11.2±6.1) points, (9.5±5.7) points, and (11.9±5.4) points in groups A, B, and C, and the decrease rates were (33.2±35.8) %, (34.5±34.1) %, and (16.7±29.5) %, respectively. The standard omeprazole test with a symptom score decrease of 2 had the best diagnostic value for GERD. After nursing intervention, the SAS and SDS scores in the group E (41±8 and 39±8, respectively) were lower than those in the group D (54±9 and 52±9, respectively), showing statistically significant differences (p<0.05). The nursing satisfaction in the group D (64%) was lower than that in the group E (96%), showing p<0.05. 

Conclusion: omeprazole test was a reliable method for the clinical diagnosis of COPD with GERD. Comprehensive nursing intervention could improve the psychological state of GERD patients and help to alleviate the clinical symptoms of patients.