Baijun Zuo1, Hongbing Qiu2, Lishan Wang1, Guojiang Chen1, Zhi Dong1, *
1Department of Orthopedics, North China Medical & Health Group Xingtai General Hospital, Xingtai 054000, Hebei Province, China - 2Department of Gynecology, Xingtai People's Hospital, Xingtai, 054000, Hebei Province, China
Introduction: To investigate the clinical efficacy of lateral tibial osteotomy (LTO) combined with knee arthroscopic debridement (KAD)in the treatment of knee osteoarthritis (KOA).
Material and method: A total of 80 patients with medial compartment osteoarthritis (MCOA) of the knee treated in our hospital were selected and divided into control group (CG) and observation group (OG) according to the differences in surgical methods. The CG (n=40) was treated with LTO alone, while the OG (n=40) was treated with LTO combined with KAD. Knee joint function, pain degree, lower limb force line and inflammatory factors were evaluated before operation and 12 weeks after operation. The complications of each group were recorded.
Results: At 12 weeks after operation, the HSS and Lysholm score of each group were increased compared with those before operation (P<0.05), and those of the OG was strikingly raised than those of the CG (P<0.05). At 12 weeks after operation, the VAS score of each groups were obviously reduced compared with those before operation (P<0.05), and that of the OG were markedly lower than that of the CG (P<0.05). Moreover, at 12 weeks after operation, mMPTA and aFTA of each groups were dramatically reduced compared with those before operation, and those of the OG were reduced than those of the CG (P<0.05). Three days after operation, the levels of IL-1β, TNF-α and PGE2 in each groups were obviously reduced compared with those before operation (P<0.05), and those in the OG were remarkably reduced than those in the CG (P<0.05). A significant difference in the total incidence of complications between the CG (5.00%) and the OG (10.00%) was not observed (P>0.05).
Conclusion: LTO combined with KAD in the treatment of KOA has better short-term efficacy than simple LTO, which can effectively improve knee function, relieve pain perception, adjust the lower limb line, reduce the level of inflammatory factors, and has high safety.
Lateral tibial osteotomy, knee arthroscopic debridement, knee osteoarthritis.