Carmen Bucuri1*, Ionel Nati2,*, Razvan Ciortea2*, Valentin Oprea1, Andrei Malutan2, Maria Rada2, Cristina Ormindean2, Flaviu Faur3, Dan Mihu2


1Dr. Constantin Papilian Emergency Military Clinical Hospital, Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca 400610, Romania - 22nd Department of Obstetrics and Gynecology, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca 400610, Romania - 32nd Department of General Surgery, “Victor Babes” University of Medicine and Pharmacy, Timişoara 300041, Romania


Cervical cancer is the third most common type of cancer that affects the female population worldwide. Conventional cytology or the Pap test represented and still represents the gold standard screening method for cervical cancer, being used on a large scale since the middle of the 20th century. Human papilloma virus which has a high tropism for squamous and metaplastic cells has been demonstrated to have a central role in the development of these lesions. This study aims is to validate the contribution of HPV infection in the occurrence of high-grade dysplastic lesions by establishing some correlations between the strains of HPV present, cervical cytology and the histopathological examination of the cervical biopsy. The access to screening methods and health education it’s the first step for early diagnosis of cervical dysplasia and cervical cancer.


Cervical cancer, HPV infection, cervical dysplasia.