CORRELATION BETWEEN CYTOLOGICAL ANOMALIES, HPV INFECTION AND HISTOPATHOLOGICAL RESULTS -THE EXPERIENCE OF DR CONSTANTIN PAPILIAN EMERGENCY MILITARY CLINICAL HOSPITAL, CLUJ-NAPOCA, ROMANIA

Carmen Bucuri^1*, Ionel Nati^2,*, Razvan Ciortea^2*, Valentin Oprea¹, Andrei Malutan², Maria Rada², Cristina Ormindean², Flaviu Faur³, Dan Mihu²

¹Dr. Constantin Papilian Emergency Military Clinical Hospital, Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca 400610, Romania - ²2nd Department of Obstetrics and Gynecology, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca 400610, Romania - ³2nd Department of General Surgery, “Victor Babes” University of Medicine and Pharmacy, Timişoara 300041, Romania

Cervical cancer is the third most common type of cancer that affects the female population worldwide. Conventional cytology or the Pap test represented and still represents the gold standard screening method for cervical cancer, being used on a large scale since the middle of the 20th century. Human papilloma virus which has a high tropism for squamous and metaplastic cells has been demonstrated to have a central role in the development of these lesions. This study aims is to validate the contribution of HPV infection in the occurrence of high-grade dysplastic lesions by establishing some correlations between the strains of HPV present, cervical cytology and the histopathological examination of the cervical biopsy. The access to screening methods and health education it’s the first step for early diagnosis of cervical dysplasia and cervical cancer.