A SYSTEMATIC REVIEW AND META-ANALYSIS OF THE EVALUATION OF THE CORRELATION BETWEEN THE VARIOUS PARAMETERS MONITORED DURING CARDIOTHORACIC SURGERY, VARIOUS DRUGS, AND POST-OPERATIVE RECOVERY

Guiqin Lu, Yuyong Guo, Hui Zhang^*

School of nursing Anhui Medical University, Hefei Anhui, 230601, China, Anhui Vocational College of City Management, Hefei Anhui, 230601, China

Purpose: To evaluate the correlation between different physiological parameters monitored and optimized during cardiothoracic surgical nursing, like the mean arterial pressure, ECG, temperature, respiratory rate, blood pressure, fluid balance, heart rate, cardiac rhythm, respiratory rate, central venous oxygen saturation (Svo2), hemodynamic parameters, and left ventricular ejection fraction of the patients, and the usage of supporting drugs like corticosteroids, muscle relaxants, and small ribonucleic acid-based drugs with the fast and healthy recovery of patients.

Methods: Electronic searches were conducted in PubMed, MEDLINE, CENTRAL databases, and the Cochrane Library from 2000 to 2022 using the appropriate keywords as per the PRISMA guidelines. Demographic summary and event data for the success rate of monitoring and optimization of different physiological parameters and effects of drugs in both experimental and control groups were extracted from the included studies and meta-analysis was performed using the RevMan software.

Results: Twelve studies with a total of 1989 patients who underwent cardiothoracic surgery were meta-analyzed. Meta-analysis provides the pooled odds ratio (OR) value of 1.24 (95% CI 1.01-1.53) with heterogenous results of a Tau2 value of 0.08, a chi2 value of 28.06, a df value of 11, an I2 value of 61%, the Z value of 2.01, and a p-value less than 0.05. Similarly, the pooled relative risk value of 1.11 (95% CI 1.0-1.23) and heterogeneity of the Tau2 value of 0.02, Chi2 value of 26.03, DF value of 11, I2 value of 58%, Z value of 2.01, and p-value less than 0.05 are comparable.

Conclusion: The present meta-analysis showed that the close monitoring and optimization of different physiological parameters and the use of supportive drugs are highly beneficial for the fast and healthy recovery of cardiothoracic surgery patients.