VALUE OF CTA COMBINED WITH NT-PROBNP IN THE DIAGNOSIS OF ACUTE PULMONARY EMBOLISM

Zhixing Fan, Zujin Xiang, Hui Wu, Jun Yang, Jian Yang^*

Department of Cardiology, the First College of Clinical Medical Sciences, China Three Gorges University, Yichang 443000, Hubei, Province, China

Objective: To explore the value of computed tomography angiography (CTA) combined with N-terminal B-type natriuretic peptide (NT-proBNP) in the diagnosis of acute pulmonary embolism (APE). 

Methods: A retrospective analysis of the clinical data of 192 APE patients in our hospital from March 2016 to May 2020. To evaluate the clinical value of CTA, plasma NT-proBNP and their combined detection in the diagnosis of APE. 

Results: In 192 patients with APE, 174 cases were positive by pulmonary artery CTA, 18 cases were missed, and the positive rate was 90.63%; 154 cases with plasma NT-proBNP>125pg/mL, the positive rate was 80.21%; the combination of two inspection methods detected APE positive 188, 4 cases were missed, and the positive rate was 97.92%. The positive rate of APE diagnosed by pulmonary artery CTA was higher than that of plasma NT-proBNP (P<0.05), and the positive rate of APE diagnosed by pulmonary artery CTA and plasma NT-proBNP was higher than that of single test (P<0.05). 

Conclusion: Plasma NT-proBNP screening combined with pulmonary artery CTA qualitative examination is of high value in the diagnosis of APE, and it is an effective non-invasive examination method.