VALUE OF COMBINED DETECTION OF AMH AND MRI IN DIAGNOSIS OF PATIENTS WITH ENDOMETRIOSIS

Sanyang Tan^{1, #}, Hong Li^{1, #}, Jun Zhang^{2, *}

¹Department of Clinical Laboratory, Haikou Maternal and Child Health Hospital, Hainan, 571100, China - ²Department of Medical Imaging, The Fourth People's Hospital of Shaanxi, Xi'an, Shaanxi 710043, China

Introduction: To explore the value of combined detection of anti-Mullerian hormone (AMH) and MR Imaging (MRI) in the diagnosis of patients with Endometriosis (EMS).

Materials and methods: 116 patients with suspected endometriosis accepted at our hospital from February 2019 to December 2021 were selected for analysis, and each patient underwent serum AMH and MRI testing. The diagnostic efficacy of AMH and MRI was analyzed according to postoperative pathological findings. The diagnostic value of combined AMH and MRI for EMS was assessed using receiver operating characteristic (ROC) curves.

Results: The diagnosis was confirmed in 97 positive and 19 negative cases among 116 patients detected by laparoscopic surgery. The sensitivity, specificity and diagnostic value of serum AMH test for EMS were 68.04, 73.68, and 0.73% respectively. The sensitivity, specificity and diagnostic value of MRI for EMS were 90.72, 84.21, and 0.87% respectively. The sensitivity, specificity and diagnostic value of MRI combined with AMH test were 95.88, 94.74, and 0.95%.

Conclusion: MRI combined with serum AMH detection can improve the sensitivity and specificity of clinical diagnosis of EMS.