POTENTIAL INAPPROPRIATE DRUG USE AND RELATED FACTORS IN ELDERLY PATIENTS WITH POLYPHARMACY

Li Zhang^{1, *}, Lixiang Zhou², Dexi Zhou³

¹Department of Pharmacy, the People's Hospital of Chizhou, Chizhou, 247100, China - ²Drug Clinical Evaluation Center, the First Affiliated Hospital of Wannan Medical College, Wuhu, 241000, China - ³Department of Clinical Pharmacy and Pharmacy Management, the First Affiliated Hospital Of Wannan Medical College, Wuhu, 241000 China

Introduction: Explore the potential inappropriate medication (PIM) of elderly patients in a hospital and its related factors.

Materials and methods: A total of 560 elderly patients with chronic diseases in Chizhou People's Hospital were selected from October 2020 to December 2020 clinical pharmacy management system Potential inappropriate medication was evaluated by the 2019 Beers standard and the China PIM Judgment Standard.

Results: A total of 560 patients were collected, mean age (75.02±6.45) years, and mean length of hospital stay (9.84±3.96) For d, (10.75±4.18)Seed, a total of 370 patients developed PIM according to the Beers criteria, with the highest incidence of proton pump inhibitors. According to the PIM judgment Standard in China, there are 393 total one patient developed PIM, of which clopidogrel the highest incidence. logistic showed that according to the Beers criteria, age and type of medication are the factors affecting the occurrence of PIM. According to logistic, according to the China PIM Judgment Standard, the type of medication affects the occurrence of PIM.

Conclusion: The incidence of PIM was high in elderly patients with multiple drugs, and the main factors affecting PIM are age and type of medication. Clinical pharmacists should pay attention to the PIM caused by the elderly patients with multiple drugs in the review of prescription and medical orders, strengthen drug monitoring, and reduce the drug damage of the elderly patients with multiple drugs.