Xinping Lei1, Xiaojuan Song2, *
1Department of Ophthalmology, Baoji People's Hospital, Baoji, Shaanxi, Province, 721000, PR China - 2Department of Endocrinology, Baoji People's Hospital, Baoji, Shaanxi, Province, 721000, PR China
Introduction: To investigate the influence factors of pupil changes after phacoemulsification and intraocular lens (ICL) implantation in patients with diabetic retinopathy (DR) and cataract, and provide more reference for clinical diagnosis and treatment.
Materials and methods: A total of 120 DR patients with cataract who underwent phacoemulsification combined with ICL implantation in our hospital from January 2019 to January 2022 were included retrospectively. Univariate and multi-variate analyses were employed to evaluate independent influence factors of postoperative pupil changes, and the correla-tion between related clinical indicators and postoperative pupil changes of patients was analyzed.
Results: Univariate analysis showed that the course and DR stage of type 2 diabetes mellitus (T2DM) were correlated with postoperative mydriasis time and diameter (P<0.05). Pearson test indicated that postoperative mydriasis time was positively correlated with the course and DR stage of T2DM (P<0.05), while postoperative mydriasis diameter was nega-tively correlated with the course and DR stage of T2DM (P<0.05). Multivariate analysis showed that the course of T2DM>10 years and proliferative DR were independent risk factors for postoperative pupil changes (P<0.05).
Conclusions: DR patients with cataracts are more likely to have contracted pupil and longer mydriasis after phacoemulsification combined with ICL implantation if the course of T2DM is longer than 10 years or DR is in prolifera-tion stage.
Cataract, diabetic retinopathy, phacoemulsification, ICL implantation.