THE EFFECT OF THREE METHODS ON DISSOLVING PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM FOR INFECTION

Li Li¹, Gao Zumei^{2, *}, Li Yuhong¹

¹The First Affiliated Hospital of Yangtze University, Trauma Hand and Foot Surgery - ²Department of Nursing, Jingzhou, Hubei, 43400, PR China

Objective: This article compares the effects of three different methods on dissolving piperacillin sodium and tazobactam sodium for infection to improve nursing efficiency. 

Methods: According to the random number table method, 120 bottles of piperacillin sodium and tazobactam sodium of the same manufacturer, batch number, and specification were divided into control group 1, control group 2, an experimental group, with 40 bottles in each group.The control group 1 shook the medicine evenly by the method of holding the "bottleneck"; The control group 2 shook the medicine evenly by the method of holding the "bottleneck and bottle";The experimental group shook the medicine evenly by the method of holding the "bottleneck and bottle" combing with knocking between corks,after shaking the vial twice up and down. The dissolution time and dissolution adequacy of the three groups of powder drugs are observed and compared. 

Results: The experimental group was better than the other two groups in terms of drug dissolution time and dissolution adequacy, and the difference between the three groups was statistically significant (P<0.05). 

Conclusion: After shaking the vial twice up and down, the method of holding the "bottleneck and bottle" combing with knocking between corks can not only shorten the dissolution time of the powder and improve the efficiency of nurses, but also make the medicine fully dissolved and ensure the accurate dosage of the medicine.