QUALITY OF LIFE AND INFLUENCING FACTORS OF LARYNGEAL CANCER PATIENTS WITH CARBON DIOXIDE LASER UNDER LARYNGEAL MICROSCOPE

Ye Chen¹, Xinhua Tang^2*

¹Department of E.N.T., Dushu Lake Hospital Affiliated To Soochow University, Suzhou 215000, Jiangsu Province, China - ²Department of E.N.T., The First Affiliated Hospital Of Soochow University, Suzhou 215006, Jiangsu Province, China

Objective: Laryngeal cancer is the second most common respiratory cancer after lung cancer and the second most commonly diagnosed tumour in the head and neck. The treatment of laryngeal cancer is supported by surgery, laser, radiotherapy, chemotherapy, and other methods, of which surgery remains the most effective treatment.

Methods: This study elaborates on the carbon dioxide laser treatment of laryngeal cancer, analyses the influence of clinical stage and surgical mode of laryngeal cancer on postoperative complications and survival rate of patients with laryngeal cancer, provides a reference for the selection of surgical mode of laryngeal cancer in different clinical stages, and discusses the influence of laryngeal cancer on the mood and psychological state of patients. This study retrospectively analyses data from 82 patients with laryngeal diseases who underwent laryngeal surgery with CO₂ laser under laryngeal microscope from May 2018 to May 2019. The surgical method involved connecting the carbon dioxide laser to the microscope through oral cannula under general anaesthesia, achieving the surgical effects of cutting and vaporization through pulsed laser, and analysing and judging the authenticity of the sample data through a chi-square test. The operations were grouped into 5 types, and the voice acoustics of the patients were detected after the operations. The survival rate and local control rate of patients with laryngeal cancer were judged and the subjective voice auditory perception assessment conducted one year after the operation.

Results: Experimental results showed that 15 of the 82 patients with glottic laryngeal carcinoma treated with carbon dioxide laser via laryngoscope had recurrence after surgery, yielding a relatively high recurrence rate of 18.29%. The 1-year postoperative survival rate and local control rate of glottis patients were both 100%, indicating that the treatment effect in the early stage of the disease was significant and the recurrence rate was not easy in the later stage.

Conclusion: Postoperative complications mainly included local infection, postoperative haemorrhage, dyspnea, dysphagia and respiratory pneumonia, of which postoperative pulmonary haemorrhage represented the main complication.