Mingming Zhang#, Chang Liu#, Erhua Wang*


Department of Anesthesiology, Nanjing Drum Tower Hospital, Nanjing 210008, Jiangsu, China


Objective: To analyze the application value of propofol in combination with remifentanil anesthesia in painless gastroscopy. 

Methods: The clinical data of 100 patients who were to undergo painless gastroscopy in our hospital from February 2021 to February 2022 were retrospectively analyzed. Based on the order of examination, they were divided into group A (propofol with remifentanil anesthesia, n=50) and group B (propofol anesthesia, n=50), with comparisons of the serum levels of pain mediators and the adverse reactions in the two groups. 

Results: The excellent and good rate of clinical anesthesia in group A was remarkably higher than that in group B (P<0.05). At the end of the examination, the serum levels of pain mediators in both groups of patients were remarkably higher than those before examination (P<0.001), with remarkably lower levels in group A than those in group B (P<0.001). After examination, the Steward recovery score of patients in group A was remarkably higher than that in group B (P<0.05), with a remarkably lower total incidence of adverse reactions in group A than that in group B (P<0.05). 

Conclusion: The combination of propofol and remifentanil anesthesia in painless gastroscopy has the advantages of low pain and high safety, with high clinical application value.


Propofol, remifentanil, painless gastroscopy, application value.