HR-MRI AND T2WI COMBINED WITH FUNCTIONAL IMAGING SIGNIFICANCE IN DIAGNOSIS OF RECTAL CANCER

Fang Zhang¹, Sibin Liu¹, Shan Xiong¹, Xiaoshuang Wang¹, Peng Xia^2,*

¹Department of Radiology, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, Hubei 434020, China - ²Department of Parasitology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, Hubei 434023, China

Introduction: Rectal cancer is a serious threat to human health, early and accurate diagnosis is very important. To evaluate the value of HR-MRI T2WI combined with functional imaging in T-staging and grading of rectal cancer. 

Material and Methods: 150 patients with rectal cancer diagnosed were analyzed. The DWI and ADC values of conventional FSE T2WI lipid suppression sequence and T2WI non lipid suppression sequence combined with functional imaging sequence were measured .

Results: The combined application of the two sequences increased the total accuracy of T staging, in which the accuracy of T1-T2 staging was 65.22% and 91.30% respectively; The accuracy of T3 phase was 61.76% and 91.18%, respectively. There was significant difference between them (P<0.05). The results showed that the ADC value was statistically significant between well, moderately and poorly differentiated adenocarcinoma (F=93.280, P<0.001). It showed the greater the ADC value, the higher the degree of tumor differentiation.

Conclusion: HR-MRI T2WI non lipid suppression sequence combined with functional imaging is superior to conventional T2WI lipid suppression sequence in rectal tumors. It can accurately stage rectal cancer, evaluate tumor invasiveness and biological characteristics, and provide a favorable basis for clinical surgeons to select surgical methods and treatment schemes.