İlkan Kayar1, Özer Birge2, *, Mehmet Sait Bakır3, Ferhat Cetin1
Osmaniye State Hospital, Department of Gynecology and Obstetrics, Osmaniye, Turkey - 2Nyala Sudan Turkey Training and Research Hospital. Department of Gynecology and obstetrics. Nyala-Darfur-Sudan - 3Akdeniz University, Department of Gynecology and Obstetrics, Antalya, Turkey
Introduction: Knowledge is limited with respect to the clinical effects of coronavirus disease (COVID-19) on ovarian functions in women of reproductive age. In this study, it was aimed to compare some hormone and vitamin levels of women in the reproductive age group, who have had COVID-19 infection and have completed their treatment, and women who have not had COVID-19.
Material and methods: Patients who applied to the gynecology outpatient clinic of the Gynecology and Obstetrics Department of Osmaniye State Hospital between January-March 2021 for various benign gynecological reasons were included in this study. Individuals who were COVID-19-positive within 3 months and had completed routine outpatient treatment without hospitalization were included in the study as the COVID-19-positive case group (n=42). The control group was selected from cases who did not have COVID-19 infection among the applicants in the same period (n=57).
Results: Compared to the control group, the mean age was significantly higher in COVID-19 positive cases (p=0.001). Compared to the control group, the estradiol (E2) and vitamin D3 levels of the COVID-19-positive group were significantly higher (p=0.041 and p=0.001, respectively), while the free T4 and free T3 values were significantly lower (p=0.001, for both).
Conclusion: It was observed that while E2 and vitamin D3 levels were increased in women who had recently suffered from COVID-19 infection and had received outpatient treatment, whereas thyroid hormones decreased slightly. It can be said that, in patients who received outpatient COVID-19 treatment, reproductive hormone levels were affected to a limited extent shortly after treatment.
Women, coronavirus disease (COVID-19), after treatment, adverse effects, hormone, vitamin D3.