Yanyan Xiao1, Ting Guo2*
1Department of Pediatrics, The Third Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421900, China - 2Department of Ultrasound Medicine, The Third Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, 421900, China
Objective: To explore the clinical value of lung ultrasound in the diagnosis and follow-up treatment of NRDS.
Methods: 170 NRDS patients admitted to the intensive care unit of our hospital from June 2018 to June 2020 were selected as the research subjects. According to the chest X-ray examination results within 6 hours of birth, the children were divided into the severe group (72 cases) and the mild group (98 cases). According to the follow-up treatment, the children were divided into the PS treatment group and the non-PS treatment group. The ultrasonic signs, pulmonary ultrasound score, and pulmonary ultrasound were analyzed and compared between the two groups before and after the PS.
Results: The mild NRDS was a small part of focal pulmonary consolidation under the pleura, with mild alveolar interstitial syndrome and bronchiolitis. Trachea inflation sign, A-line disappeared, pleural line blurred, and lung sliding sign was observed, no lung pulsation sign was found. The ultrasound of severe NRDS is characterized by large-scale consolidation of the lung field, obvious alveolar interstitial syndrome and bronchial inflation syndrome, the disappearance of A-line and pleural line, a small amount of pleural effusion, pulmonary pulsation syndrome can be observed, and no pulmonary sliding syndrome can be observed. The pulmonary ultrasound score of the severe group was significantly higher than that of the mild group (P < 0.05), and the sensitivity and specificity were better; the examination methods of pulmonary ultrasound and X-ray could effectively judge mild and severe NRDS (P > 0.05). The PS score of the mild group and the severe group before treatment was significantly higher than that of 12 hours and 24 hours after the treatment (P < 0.01 or P < 0.001). The pulmonary ultrasound results of mild and severe DRDS were significantly improved 12 hours and 24 hours after the treatment; the two differences between ultrasound and X-ray were 0.688 (P > 0.05) and 0.591, respectively (P > 0.05).
Conclusion: Acoustic evaluation of mild, severe, and curative effect of NRDS was beneficial. Pulmonary ultrasound score can be used as an evaluation index of NRDS condition and after the treatment. PS treatment of NRDS can significantly decrease its mortality and complication rate.
NRDS, Lung Ultrasound, Alveolar Surfactant, Score, Clinical Application.