Yanwen Zheng, Haiyan Wu*
Department of Respiratory, the First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, 311200, Zhejiang, China
Introduction: Large cell lung cancer (LCLC) is a rare and unique histopathological type of bronchial lung cancer with highly malignant clinical behavior.
Materials and methods: In this study, we report a 76-year-old man with a 15-year history of hypertension who smoked more than 1 pack per day for more than 50 years.Due to pulmonary space occupying lesions found for more than 3 months after the discovery of lung lesions, cough sputum and hemoptysis for 1 month. Primary LCLC with squamous cell carcinoma (SCC) was diagnosed by tracheoscopy and immunohistochemistry (IHC).
Results: EP regimen (etoposide 160mg D1, D2, D3 + cisplatin 60mg D1, D2) was given for 4 cycles of chemotherapy, during which GTV (mass) was given: 6450cGy/ 30F, PTV was 0.8cm of mass expansion, and the dose of 5400cGy/ 30F was given for 2 cycles of radiotherapy.
Conclusion: The improvement was evident after radiotherapy and chemotherapy.
Primary large cell lung cancer, radiotherapy and chemotherapy, large cell neuroendocrine carcinoma, squamous cell carcinoma, non-small cell lung cancer.
10.19193/0393-6384_2022_2_193