CLINICAL OBSERVATION OF NANOCARBON TRACER ASSISTED PARATHYROIDECTOMY IN THE TREATMENT OF SECONDARY HYPERPARATHYROIDISM

Hengfeng Cui¹, Lisheng Wang¹, Weiwei Ji^{1, *} 

¹Department of General Surgery, Yancheng third people’s Hospital, the affiliated hospital of Jiangsu vocational college of Medicine, Yancheng 224000, Jiangsu Province, China

Objective: To study the clinical effect of nanocarbon tracer assisted parathyroidectomy in the treatment of secondary hyperparathyroidism. 

Methods: A total of 104 SHPT patients admitted to our hospital from September 2018 to September 2020 were selected as the main research subjects. Using the random number table method, the patients were divided into a study group (52 cases) and a control group (52 cases). The control group patients underwent a standard parathyroidectomy (PPTX), whilst the study group received PPTX treatment assisted with nanocarbon tracer. The intraoperative and postoperative indicators, the number of parathyroidectomies, the rate of misresection of lymph nodes, iPTH and blood calcium levels, and postoperative complications were compared between the groups. 

Results: The 52 patients in the study group were injected with carbon nanotracer during the operation. The injection position was correctly determined and there was no leakage. Apart from the parathyroid glands, none of the other tissues were stained black. There was no significant difference between the two groups in the amount of intraoperative time and intraoperative bleeding and the length of postoperative hospital stay (P>0.05). The preoperative ultrasound showed no significant difference in the number of parathyroid glands between the study group and the control group (P>0.05). The misresection of lymph nodes in the study group was lower than that in the control group during the operation (P<0.05); the number of parathyroidectomies in the study group was higher than that for the control group (P<0.05); there was no significant preoperative difference in blood calcium levels and iPTH levels between the study group and the control group (P>0.05), but the postoperative blood calcium levels and iPTH levels of patients in the study group were significantly lower than those in the control group (P<0.05); the total incidence of postoperative complications in the study group was significantly lower than that in the control group (P<0.05). 

Conclusion: The clinical effect of nanocarbon tracer assisted PPTX in the treatment of SHPT is significant, not only for accurately locating the position of the parathyroid and reducing the incidence of misdiagnosis of the lymph nodes, but also in reducing the occurrence of postoperative complications.