APPLICATION OF NANOPARTICLES IN SYNCHRONOUS SIGNAL TRANSMISSION FOR MINIMALLY INVASIVE SURGERY AND DRUG DELIVERY IN RENAL FAILURE

Xuelian Luo¹, Chengsheng Wu^{2, *}, Zhiwen Zhu¹, XiaopingYao³, Wenting Yao¹

¹Department of Medicine, Tongling Polytechnic, Tongling, 244061, China - ²Department of Surgical, Tongling Municipal Hospital, Tongling, 244000, China - ³Department of Radiology, Tongling People's Hospital, Tongling, China

The synchronous signal transduction and drug delivery by nanoparticles can improve the completion of treatment and surgery for minimally invasive renal failure. The nanoprobe is constructed by loading different signal molecules, photosensitizers, acoustic sensitizers, and thermosensitive through the method of double emulsion or film hydration. The near-infrared confocal endoscope molecular image diagnosis and treatment equipment are designed based on the nanoprobe, through which the intraoperative high-frequency image is obtained. In this study, nano carbons are used to deliver drugs. Further, the effect of the drug on reducing creatinine and urea is investigated. The experimental results show that the designed nanomolecular image probe has good stability, and the simulated signal transmission waveform is consistent with the transmission waveform of the principal analysis. Applying the proposed method to the minimally invasive surgery of renal failure, it is found that the success rate and image signal transmission efficiency of the minimally invasive surgery of patients 1-5 are higher than 99.5%, and the operation image transmission accuracy is high; hence, the operation effect is excellent. The effect of the drug transferred by nano carbon is significant and is associated with a decrease in creatine and urea.