Vitamin D Level In COVİD-19 Positive Patients

Mine Öztürk

Department of Endocrinology and metabolism, KTO Karatay University Medicine Faculty Hospital, Konya, Turkey

Objective: The aim of this cross-sectional study. To draw attention to the importance of vitamin D supplementation in the treatment and prognosis of COVID-19 patients, to make a scientific contribution to the COVID-19 pandemic. 

Methods: With the onset of the COVID-19 epidemic, patients who came to our hospital in the last 18 months and had the  COVID-19 test were screened. The test result is positive or negative; 413 patients whose vitamin D (ng / ml) levels were examined were included in the study. Vitamin D (ng / ml) levels of 133 patients with positive COVID-19 test and 280 patients with negative COVID-19 test were compared.

Results: 413 patients were included in the study. 204 (49.3%) patients were female and 209 (50.7%) patients were male. 133 (32.2%) patients were COVID-19 positive, 280 (67.8%) patients were COVID-19 negative. The mean age of  COVID-19 positives was 48.4 (16.8) and the mean age of COVID-19 negatives was 45,6(17.8). The mean of vitamin D of  COVID-19 positives was 19.8 (13.3), and the mean of vitamin D of  COVID-19 negatives was 29.5(15.8).  Of the 133  COVID-19 positive patients, 71 (%53.3) were female and 62 (%46.6) were male. Of the 286  COVID-19 negatives patients, 133 (%46.5) were female and 147 (% 53.5) were male. According to the Mann-Whitney test, the mean rank of  COVID-19 negatives is 235.7, and the mean rank of positives is 146.4. Z-score was -7.11, p-score was 0.00.

Conclusions: The main finding of this cross-sectional study conducted in our hospital is; COVID-19 positive patients have lower serum vitamin D than COVID-19 negative patients. This new finding provides a scientific basis for vitamin D replacement in  COVID-19 patients.