RELATIONSHIP ANALYSIS BETWEEN HUMAN ABO BLOOD GROUP AND PANCREATIC DUCTAL ADENOCARCINOMA

Wang Lianmin^{#, 1}, Shi Yanmei^{2, #}, Tang Zhiyi^{2, #}, Liu Yaqiong², He Haiyu², Wang Tao¹, Su Kun¹, Wang Kun¹, Chang Jiang^{*, 2}, Wu tao^{*, 1}

¹Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Kunming Medical University, Kunming, 650101, Yunnan, People's Republic of China - ²Department of Gastroenterology, The Second Affiliated Hospital of Kunming Medical University, Kunming, 650101, Yunnan, People's Republic of China

Introduction: We aimed to analyze the relationship between human ABO blood group and pancreatic ductal adenocarcinoma (PDAC). 

Materials and methods: A total of 61 patients with pancreatic ductal adenocarcinoma confirmed by postoperative pathological diagnosis in the Second Affiliated Hospital of Kunming Medical University from January 2003 to December 2017 were enrolled in this retrospective study. Data, including gender, age, ABO blood type, tumor type, tumor differentiation, lymph node metastasis and organ infiltration, were collected and analyzed. 

Results: Among the 61 patients, there were 21 patients with type A blood, 16 with type B blood, 9 with type AB blood and 15 with type O blood. Moreover, patients with type A blood had a higher degree of tumor differentiation than those with non-A type blood (P=0.023). In patients with type B blood, there were more number of metastatic lymph nodes than the other groups (P<0.05). 

Conclusion: The patients with type A blood have a higher risk of PDAC than those with other types of blood.