NASOPHARYNGEAL CARCINOMA TREATMENT EFFECT ON THE COGNITIVE FUNCTION OF THE ATTENTION NETWORK: AN EXAMPLE FROM THE COASTAL CITY OF HANGZHOU (CHINA)

Shuang Zheng¹, Jincheng Li¹, Hongying Luo², Qing Lan², Kainan Shao³, Fenglei Du^3*

¹Hangzhou Dianzi University, School of Media and Design, Hangzhou, Zhejiang 310018, China - ²University of South China, Faculty of nuclear science and technology, Hengyang, 421001, China - ³The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China

 Objective: This study mainly to explore the effect of comprehensive treatment in Hangzhou (China) on cognitive function of attention network in patients with nasopharyngeal carcinoma.

Methods: Patients with locally advanced nasopharyngeal carcinoma who were initially diagnosed as the pre-treatment group were collected as the pre-treatment group in Hangzhou (China), and the patients who were reexamined within more than half a year after treatment were the post-treatment group. All patients received behavioral tests of attention network cognitive function. The processing efficiency of three sub-networks (executive control network, alertness system and orientation network) of cognitive function of patients' attention network was compared horizontally.

Results: After treatment, the score and ratio of processing efficiency of executive control network in the group after treatment were significantly lower than those in the group before treatment, while the scores and score ratios of alertness system and oriented network processing efficiency did not change significantly. Conclusion: After treatment, the processing efficiency of the alert system and orientation network of NPC patients did not change significantly in Hangzhou (China), but the processing efficiency of the executive control network was improved.

Conclusion: We determined that the pneumococcal vaccine, which is mainly administered in family medicine centers, has a positive effect on the course of COVID-19, and adult immunization should be given importance in every period.