CLINICAL EFFICACY AND SAFETY OF DIET CONTROL THERAPY COMBINED WITH DIGESTIVE ENZYME PREPARATION IN TREATING FUNCTIONAL GASTROINTESTINAL DISORDERS

Xiaoyu Xuan^{1, *}, Jingli Xuan²

¹Department of Gastroenterology and hematology, Chengde Central Hospital, 067024, Chengde City, Hebei Province, China - ²Yongshun Community Health Service Center, 064499, Qian’an City, Hebei Province, China

Objective: To explore the clinical efficacy and safety of diet control therapy combined with digestive enzyme preparation in treating functional gastrointestinal disorders (FGIDs). 

Methods: The clinical data of 90 FGIDs patients treated in our hospital (01, 2019 to 01, 2020) were selected for the retrospective analysis, and the patients were divided into the experimental group (EG, n=45) and control group (CG, n=45) according to the admission order. Patients in CG received routine treatment and those in EG accepted diet control therapy combined with digestive enzyme preparation, and various clinical indicators were compared between the two groups. 

Results: Compared with CG after treatment, EG obtained obviously lower clinical symptom score, PHQ-9 score, GAD-7 score and total incidence rate of adverse reactions (p<0.05), and significantly higher serum biochemical indexes (p<0.001). 

Conclusion: Combining diet control therapy with digestive enzyme preparation has exact efficacy and higher safety, which is a reliable scheme to improve the clinical symptoms in FGIDs patients. This strategy greatly improves patients’ quality of life. Further research will be conducive to providing a better solution for such patients.