Wenbin Liang1, Jing Shen2, Yuanling Zhang3, Hongbing Li3*, Bangxing Yu4*


1Department of Gynecological Surgery, Wuhan Wudong Hospital, Wuhan 430084, Hubei, China - 2The First Department of Psychiatry, Wuhan Wudong Hospital, Wuhan 430084, Hubei, China - 3Department of Emergency, Guiyang First People's Hospital, Guiyang 550002, Guizhou, China - 4Department of Neurology, Taizhou First People's Hospital, Taizhou318020, Zhejiang, China


Introduction: The therapeutic effects of conventional craniotomy under the intervention of humanized nursing model and microscopic resection on brain glioma were compared. 

Materials: 80 patients with brain glioma were selected and randomly divided into Ctrl group performed with conventional craniotomy (n=40) and Test group receiving microscopic resection (n=40). Methods: during the perioperative period, humanized nursing intervention was carried out. Perioperative indexes, clinical efficacy, activities of daily living (ADL), cognitive function, quality of life, adverse emotions, and the incidence and relapse rate of complications were compared. Besides, the risk factors of postoperative recurrence were analyzed. According to the results, intraoperative blood loss, operation time, incision length, postoperative time to ambulation, and length of stay of the patients in Test group reduced compared with those of patients in Ctrl group.

Results: Total effective rate (38/95.0% vs 29/72.5%), ADL score, and the scores for cognitive function and quality of life increased. The score for adverse emotions, the incidence of complications (5/12.5% vs 2/5.0%), and relapse rate (11/27.5% vs 2/5.0%) reduced (P<0.05). Multivariate Logistic regression analysis demonstrated that age over 45, tumor diameter greater than 6cm, high-level pathological grades (III~IV), and craniotomy were the independent risk factors of postoperative recurrence of brain glioma (P<0.05).

Conclusion: Humanized nursing intervention-based microscopic surgical treatment for brain glioma was featured with not only small trauma, but also with better postoperative cognitive function, ADL, quality of life, excellent clinical efficacy, and high surgical safety.


brain glioma, microscope, craniotomy, humanized nursing, recurrence.