ESTABLISHMENT AND CLINICAL SIGNIFICANCE OF MULTIPLE ORGAN DYSFUNCTION SYNDROME EARLY WARNING SCORE IN SEVERE TRAUMA PATIENTS

Lian Zhu¹, Bo Wang¹, Haili Wang¹, Yan Yan^{2, *}

¹Department of Orthopedic Truma Centre, 3rd Hospital of Hebei Medical University, Shijiazhuang, PR China - ²Department of Emergency, 3rd Hospital of Hebei Medical University, Shijiazhuang, PR China

 Objective: To explore the establishment and clinical significance of the multiple organ dysfunction syndrome (MODS) early warning score in severe trauma patients. 

Methods: From January 2018 to January 2019, 60 patients with severe trauma were selected and divided into two groups according to treatment results, 30 in each group. The control group consisted of non-MODS patients, while the observation group consisted of MODS patients. The serum procalcitonin (PCT), C-reactive protein (CRP), white blood cell (WBC) index, neutrophil granulocyte and blood glucose of the two groups were compared in different stages. The severity of trauma and chronic health were evaluated, and multiple factor regression analysis of MODS was performed. 

Results: The levels of PCT, CRP, WBC and neutrophils in the observation group were higher than those in the control group (P>0.05). The indexes of blood glucose, insulin, lactate and pyruvate in the observation group were higher than those in the control group (P>0.05). The indexes of injury severity score, acute physiology and chronic health evaluation (APACHE) II, Glasgow coma core, sequential organ failure assessment (SOFA) and activated partial thromboplastin (APIT) in the observation group were higher than those in the control group (P>0.05). The score of APACHE II ≥9 was 1.047, the score of APIT >40s was 1.305, the score of SOFA ≥7 was 1.521 and the score of SOFA 4-6 was 1.147. The MODS early warning indicators were more effective than other scoring methods (P>0.05). 

Conclusion: The application of the MODS early warning score in patients with severe trauma has a key effect on helping clinicians to find and treat as early as possible. It can reduce the risk of complications, ultimately reduce the incidence of MODS, and has high clinical value.