ANALYSIS ON THE APPLICATION VALUE AND SAFETY OF CT-GUIDED PERCUTANEOUSLY TRANSTHORACIC LUNG BIOPSY IN THE DIAGNOSIS OF PULMONARY MALIGNANCY

Hongyong Cai^*, Shenghong Yang, Di Ke

Affiliated Hospital of Zunyi Medical University, Zunyi 563003, China

Objective: The purpose of the study was to investigate the clinical application value and safety of CT-guided percutaneously transthoracic lung biopsy (CT-GPLB) in the diagnosis of pulmonary malignancies in patients. 

Methods: A total of 120 patients who underwent CT-GPLB and were diagnosed with pulmonary malignancies in our hospital from January 2019 to January 2020 were selected as study subjects. The relationship between CT-GPLB sensitivity and complication rate (CR), patients’ age, lesion size as well as puncture depth was analyzed, and the results of pathological distribution of puncture were summarized. 

Results: There were 118 patients diagnosed with pulmonary malignancies by CT-GPLB, with the sensitivity of 98.3 %; the patients (≤30 years old and >70 years old) had the sensitivity of 100.0 %, the patients (>30 years old and ≤50 years old) had the sensitivity of 97.1 %, and the patients (>50 years old and ≤70 years old) had the sensitivity of 98.2 %; the patients with the lesion size (>5 cm and ≤7 cm, and >7 cm) had the sensitivity of 100.0%, the patients with the lesion size (≤2 cm) had the sensitivity of 96.0 %, and the patients with the lesion size (>2 cm and ≤5 cm) had the sensitivity of 97.1 %; the patients with the puncture depth (>7 cm and ≤9 cm, and >9 cm) had the sensitivity of 100.0%, the patients with the puncture depth (≤ 4 cm) had the sensitivity of 98.5%, and the patients with the puncture depth ( >4 cm and ≤7 cm) had the sensitivity of 96.9%, with no significant differences (P<0.05); the occurrence rate of pneumothorax and hemoptysis in patients was 14.2% and 18.3%, respectively, and the patients had no symptoms after treatment, with no death; lesion size and puncture depth were both the key factors affecting patients’ CR. 

Conclusion: CT-GPLB, with high safety and feasibility, has high application value in the diagnosis of pulmonary malignancies, and there is a close relationship between CR and lesion size as well as puncture depth.