STUDY ON EFFECT OF STANDARDIZED INSULIN INJECTION TECHNIQUE ON MENTAL STATUS AND BLOOD GLUCOSE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Yanyan Wang¹, Qirong Wei¹, Xinyan Xu^{2, *} 

¹Department of Endocrinology, Affiliated Hospital of Northwest University for Nationalities, Department of Endocrinology, The second people's Hospital of Gansu Province, Lanzhou, 730030, Gansu, China - ²Training Center of Affiliated Hospital of Northwest University for nationalities, Training center of the second people's Hospital of Gansu Province, Lanzhou, 730030, Gansu, China

Objective: The purpose was to explore the effect of standardized insulin injection technique on mental status and blood glucose in patients with type 2 diabetes (T2DM). 

Methods: 100 T2DM patients who treated with insulin injection in our hospital from February 2018 to May 2019 were selected as the study subjects, and divided into control group (n=50) and experimental group (n=50) according to their order of admission. Patients of the control group received conventional insulin injection treatment, while those of the experimental group were treated with standardized insulin injection technique to analyze related indexes of mental status and blood glucose in two groups of patients. 

Results: (1) After treatment, SAS and SDS scores significantly decreased in both groups of patients, and the SAS and SDS scores of the experimental group (50.35±7.28, 46.15±6.21) were significantly lower than those of the control group (56.22±7.05, 50.33±6.03), with statistical significance (T=4.10, 3.41; P<0.001). (2) After treatment, fasting plasma glucose (FPG), 2h postprandial plasma glucose (2h PPG) and glycosylated hemoglobin (HbA1c) significantly decreased in both groups of patients, and the FPG level (8.05±1.22 mmol/L), 2h PPG level (10.32±1.82 mmol/L) and HbA1c level (6.09±0.92%) of the experimental group were significantly lower than (9.15±1.33) mmol/L, (12.02±1.90) mmol/L and (7.12±0.95)% of the control group, with statistical significance (T=4.31, 4.57, 5.51; P<0.001). (3) The occurrence of adverse events such as subcutaneous lipomatosis, needle reuse and hypoglycemia in the experimental group was significantly lower than that in the control group, with statistical significance (T/X2=16.00, 6.32, 12.25; P<0.001). 

Conclusion: Standardized insulin injection technique for T2DM patients can improve their adverse mental status and have a positive effect on the long-term stability of blood glucose control.