Bilger Çavuş¹, Türker Çavuş²
¹Bingöl State Hospital Gastroenterology Department - ²Kırklareli State Hospital Internal Medicine
Introduction: RDW, which can be demonstrated with a simple blood test, has been shown to be used as a prognostic and diagnostic tool in many inflammatory and cancer related diseases. There are studies on gastric cancer, esophageal cancer and RDW in gastrointestinal bleeding, especially in diseases of the gastrointestinal tract. Red blood cell distribution width’s (RDW) relationship with many diseases and inflammatory processes has been investigated but there is no study in the literature to show its relationship with H. Pylori. We aimed to investigate the relationship between RDW and H. Pylori in this study.
Materials and methods: In our study, we included 229 patients who underwent gastroscopic evaluation for various reasons and gave antral biopsies. Patients were divided into two groups based on whether H. pylori was detected or not by pathological evaluation.
Results: In our study, 229 patients (117 male) were included. The H. pylori positivity was determined as 39.3% in all patients, and this rate was 36.8% in males and 42% in females. In H. pylori-positive patients, the mean RDW value was 13.84, and the mean RDW value was 13.83 in the H. pylori-negative group (p = 0.46). The mean RDW value of the patients with intestinal metaplasia (IM) was 14.39, whereas it was 13.73 in the H.pylori-negative group (p=0.03). The mean RDW value of patients who had atrophy based on their pathological evaluation was 14.15 and the mean RDW value was 13.73 in the patients without atrophy (p=0.39).
Conclusions: Detection of H. Pylorin in the gastric mucosa alone does not cause a change in RDW, while it leads to a higher RDW ratios when intestinal metaplasic changes occur. Therefore, if individuals with H.pylori positivity are accompanied by high RDW, care should be taken in terms of IM in endoscopic evaluation.
H. pylori, blood, RDW, intestinal metaplasia.
10.19193/0393-6384_2020_6_514