THERAPEUTIC EFFICACY OF TRANSJUGULAR INTRAHEPATIC PORTOSYSTEMIC STENT SHUNT ON CIRRHOTIC PORTAL HYPERTENSION

Zhihui Liang, Liang Li, Jinglei Liu, Liming Cao, Jianyu Liu, Jingliang He^*

Department of Radiology, The 980 Hospital of PLA Logistic Force, Shijiazhuang 050082, P.R. China

Backgroud: This study aimed to explore the therapeutic efficacy of transjugular intrahepatic portosystemic stent shunt (TIPSS) on cirrhotic portal hypertension. 

Materials and methods: A total of 117 patients with cirrhotic portal hypertension admitted to our hospital from February 2014 to February 2016 were enrolled for prospective analysis. Among them, 61 patients were treated with TIPSS as the research group, while the other 56 patients were treated with percutaneous transhepatic variceal embolization (PTVE) treatment as the control group. The clinical efficacy, incidence of adverse effects, liver function, and prognosis were compared between the two groups. 

Result: There was no significant difference in the incidence of adverse effects and prognosis between the two groups (all P>0.050). The clinical treatment rate of the research group was significantly higher than that of the control group (P<0.001). And liver function and blood flow were significantly better than the control group (P<0.001). 

Discussion and conclusion: TIPSS is more effective than PTVE in the treatment of patients with cirrhosis and portal hypertension, but it is necessary to pay close attention to the patient’s blood pressure reduction to prevent hepatic encephalopathy.