Eosinophil to lymphocyte and Neutrophil to lymphocyte ratio as a new predictive and prognostic factor at the both asthma and allergic rhinitis

Erkan Yıldız*, Fatih Alaşan**, Selçuk Kuzu***, Buğra Koca***

*Department of Otorhinolaringology, Afyonkarahisar Şuhut State Hospital,Afyonkarahisar, Turkey - **Department of Chest Diseases, Afyonkarahisar Şuhut State Hospital, Afyonkarahisar, Turkey - ***Department of Otorhinolaringology, Healty Science University Hospital, Afyonkarahisar, Turkey - ****Department of  Medical Biochemistry, Healty Science University Hospital, Afyonkarahisar, Turkey

Introduction: A complete blood count is a cost-effective test that is easy to study. The neutrophil/lymphocyte and eosinophil / lymphocyte ratio calculated from this test are used in both prognosis and classification in some diseases with chronic inflammation. In our study, neutrophil/lymphocyte and eosinophil / lymphocyte ratio of patients with allergic rhinitis and asthma together with asthma or will be examined.

Materials and methods: A total of 600 patients with asthma, allergic rhinitis and allergic rhinitis and asthma who did not have 3 diseases were selected from 20-65 years old patients who applied between 2017 and 2019 for this study. These patients were divided into 4 equal groups of 150 people who were sex and age-matched. Group 1 is the control group, Group 2 is only allergic rhinitis disease, Group 3 has only asthma, and Group 4 has both allergic rhinitis and asthma. All patients with asthma and allergic rhinitis were selected from these patients. Hemogram of these patients were analyzed retrospectively. Age, sex, neutrophil, eosinophil, lymphocyte values and rates were recorded.

Results: In terms of neutrophil to lymphocyte ratio, a significant difference was observed when compared with the control group of allergic rhinitis group, asthma group and allergic rhinitis + asthma group. AR + Asthma group did not show a significant difference in terms of NLR compared to AR and asthma group. A significant difference was observed in terms of eosinophil to lymphocyte ratio compared to the control group of allergic rhinitis group, asthma group and AR + asthma group. No significant difference was observed between the AR + asthma group compared to AR and asthma group. (p> 0,088, p> 0,073)

Conclusion: For the NLR group, no difference was observed between the patients with asthma and allergic rhinitis. For ELR, there was no difference in terms of only asthma or allergic rhinitis.