Yilmaz Tezcan*, Mehmet Koc**


*Ankara Yıldırım Beyazıt University Medical School, Department of Radiation Oncology - **Necmettin Erbakan University Meram Medical School, Department of Radiation Oncology


Objective: The aim of the present study is to prospectively evaluate the quality of life in women with breast cancer who underwent radiotherapy through field-in-field intensity modulated radiotherapy technique (FIF-IMRT) after mastectomy or breast-conserving surgery (BCS).

Methods: The quality of life of 67 women diagnosed with breast cancer was evaluated by using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30) and breast cancer supplementary measure (QLQ-BR23). The evaluations were performed twice as before the radiotherapy and after the radiotherapy. 

Results: The total number of the patients analyzed was 67 and the median age was 46 (27-66) years. Mastectomy was performed in 59.7% (n=40) and breast-conserving surgery was performed in 40.3% (n=27) of the patients. Sentinel lymph node dissection was performed in 16.4% and axillary dissection was performed in 83.6% of the patients. 47 women were early stage and 20 women were stage III. The median number of chemotherapy cures was 6, the median FIF-IMRT dose was 50 Gy. All the patients were asked to reply to 30 questions in the QLQ-C30 question scale and 23 questions in the QLQ-BR23 question scale.

Conclusions: It was seen that among a total of 53 scores of EORTC QLQ-C30 and QLQ-BR23, there was a negative effect on only 6 scores in women patients with breast cancer who underwent FIF-IMRT. This negative effect was particularly observed in postmenopausal women who underwent mastectomy and axillary dissection (p≤0.05). In the acute period after radiation therapy did not affect the other functions on the quality of life (p>0.05).


Breast cancer, quality of life, mastectomy, breast symptoms, FIF-IMRT.