Yasar Keskin*, Berna Urkmez**


*Bezmialem Vakif University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Istanbul, Turkey - **Haydarpasa Numune Education and Research Hospital, Department of Physical Medicine and Rehabilitation, Istanbul, Turkey


Introduction: Fibromyalgia syndrome (FMS) is a non-inflammatory disease characterized by chronic widespread pain and sensitive spots of 3 months duration. Chronic musculoskeletal pain and fatigue are common symptoms in hypothyroidism. In this study, we aimed to investigate whether hypothyroidism in patients with fibromyalgia affects the severity and symptoms of fibromyalgia.

Materials and method: We conducted a cross-sectional. Ninety FMS patients between the ages of 25 and 65 years were included. The patients were divided into groups with hypothyroidism (60 patients) and without hypothyroidism (HT) (30 patients). Patients diagnosed with FMS according to the American College of Rheumatology (ACR) Fibromyalgia 2013 alternative diagnostic criteria (2013 AltCr). Pain intensity was assessed with Symptom Impact Questionnaire (SIQR) and Pain location inventory (PLI). Patients' depression was assessed by the Beck Depression Inventory (BDI). The quality of life of the patients was assessed by short form-12 (SF-12).

Results: SF-12 mental and physical scores of patients with FMS and HT were significantly lower (P: <0.001, P: 007, respectively). Likewise, PLI score and SIQR Symptoms score were statistically significant in FMS and HT group. However, there was no difference between the Beck depression scale scores of the groups.

Conclusion: HT affects both quality of life and pain severity negatively in patients with FMS. When planning the treatment of patients with FMS, it should be kept in mind that other systemic diseases other than the disease itself may affect pain and quality of life in fibromyalgia patients.


Fibromyalgia, hypothyroidism, quality of life, Beck Depression Inventory.