Cristina Tornali*°, Mariano Martini**, Flavio Alfio Giangiuseppe Vecchio****, Nicola Luigi Bragazzi**, Andrea Pratic****, Agata Polizzi***, Martino Ruggieri****, Ignazio Vecchio****


*Department of Biomedical and Biotechnological Sciences, University of Catania, Italy - **Department of Health Science - Section of Hygiene and Global Health, University of Genoa, Italy - ***Department of Educational Sciences, University of Catania, Italy - ****Department of Clinical and Experimental Medicine, University of Catania, Italy


Down syndrome is a genetic syndrome related to trisomy 21, and characterized by intellectual and adaptive deficiencies, facial deformities, cardiopathiacenitis and hypotonia that determine a specific cognitive behavioral phenotype.

The behavioral and psychiatric cognitive phenotype and its evolutionary profile impose bioethical considerations in the down to promote better and personalized clinical and relief, diagnostic and therapeutic strategies to favor an adequate insertion of the down in the scholastic and work environment


cognitive disabilities, bioethics, Down syndrome.