Wei Ren#, Li Xu, Chen Zhao, Wei Chen, Jun Jiang, Lei Lan
Department of Nephrology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China
Objective: The aim of this study was to investigate the clinical features and risk factors of peritoneal dialysis-associated frequent peritonitis (PD-FP).
Methods: The clinical data of patients who underwent peritoneal dialysis catheterization and subsequent continuous ambulatory peritoneal dialysis were retrospectively analyzed. The patients were grouped according to the frequencies of peritonitis events that occurred within 1 year (group 1, ≥2 times; group 2, 1 time) to compare their clinical and laboratory data and analyze the related risk factors.
Results: Groups 1 and 2 consisted of 30 and 57 cases of infective peritonitis, respectively. Compared with group 2, group 1 had significantly higher ratios of patients with abnormal blood pressure, high body mass index (BMI), immunoreactive parathyroid hormone, non-in-time treatment, insufficient anti-infective treatment, extubation, and Gram-negative bacteria, respectively (P < 0.05). However, the hemoglobin and serum albumin levels in group 1 were significantly decreased, as compared with those in group 2 (P < 0.05).
Conclusion: Logistic analysis revealed that high BMI, severe hypertension, low hemoglobin level, and low serum albumin level were the risk factors of PD-FP. Improvement of anemia, malnutrition, high BMI, or volume overload can contribute to the prevention and control of PD-FP.
frequent peritonitis, peritoneal dialysis, risk factors.