DongDong Yu1, Hui Cao1, Yuxiang guan2,*


*Graduate School of Anhui University of Chinese Medicine, Hefei, PR China - **The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, PR China


Diabetes mellitus is one of metabolic diseases characterized by elevated blood sugar, which has seriously threaten human health. At present, traditional Chinese medicine treatment of diabetes and its complications has the characteristics of multi-target, owning unique advantages in the prevention and treatment of diabetes. Astragaloside is an important active ingredient of astragalus membranaceus. With the analysis of its pharmacological effects, it can improve the function of endothelial cells and neovascularization, promote the increase of neural stem cells, increase the immune function of the body, and also have anti-inflammatory and anti-oxidative effects. Its application in diabetes mellitus can improve pathological damage by regulating blood sugar level, such as diabetic retinopathy and diabetic cardiomyopathy. In this paper, the pharmacological effects of astragaloside IV in the diabetes mellitus treatment and its complications were analyzed in order to provide relevant basis for clinical research.


Astragaloside, diabetes mellitus, complications, pharmacological effects.