STUDY ON THE EFFECT OF 6 ITEMS OF THE DETECTION OF LUNG CANCER MARKERS COM- BINED WITH MYRIAN IN SCREENING EARLY LUNG CANCER IN SMOKING POPULATION

Yinwen Zhang, Yongfeng Ma*, hao Jiang

Cangzhou People’s Hospital, Cangzhou, Hebei, 061000, China

 Objective: it is to investigate the clinical effect of serum CEA, CA153, CYFRA21-1, CA125, NSE, and CA199 in the application of Myrian imaging reconstruction technique in screening early lung cancer after multislice spiral CT examination in smoking population. Methods: select a total of 100 smoking patients suspected of having early lung cancer after the screening of CEA, CA153, CY- FRA21-1, CA125, NSE, and CA199 in Department of Respiratory Medicine of our hospital from January 2006 to 2007. First, 512-slice spiral CT was used for detection and screening. Then, Myrian image reconstruction technique was applied for testing and screening. The patients were followed up for 5 years and their incidence of lung cancer was counted. The specificity, accuracy and sensitivity of

Myrian imaging reconstruction and conventional 512-slice spiral CT were evaluated.

Results: the sensitivity, specificity, Youden index and accuracy of Myrian reconstruction were 95.45%, 81.82%, 77.27% and

82%, respectively; the sensitivity, specificity, Youden index and accuracy of 512-slice spiral CT were 92.42%, 63.64%, 56.06% and 90% respectively. However, the different has no statistical significance.

Conclusion: The use of Myrian image reconstruction technique can be used as one of the tools for clinical auxiliary diagnosis in the diagnosis of early lung cancer.