Wei Liu1, *, Hongbo Wu1, Li ZHou1
Pediatric center , Beijing Luhe Hospital, Affiliated to Capital Medical No. 82 Xinhua south road, Tongzhou district, Beijing, 101100
Purpose: To investigate the effects of fine particulate matter (PM2.5) on inflammatory injury and immune function in young rats.
Results: The expression level of IL-8 in the experimental group was significantly higher than that in the control group (p < 0.05). Compared with the control group, PM2.5 significantly inhibited the proliferation of splenocytes and induced apoptosis (p < 0.05).
Conclusion: PM2.5 provokes persistent inflammatory injury and aggravates immune injury in young rats.
PM2.5, IL-8, Lymphocytes, Apoptosis
10.19193/0393-6384_2019_2_157