RELEVANCE BETWEEN RANDOM BLOOD GLUCOSE LEVEL OF SPONTANEOUS CEREBRAL HEMORRHAGE IN ACUTE STAGE AND SEVERITY OF DISEASE AS WELL AS PROGNOSIS

Guo HuanG1, JiandonG Zuo2*

1Department of Military Surgery, Lianshui County People's Hospital, Lianshui County, Jiangsu Province, 223400, China - 2Department of Neurosurgery, The Affiliated Huai’an Hospital of Xuzhou Medical University, Huai’an, Jiangsu Province, 223001, China

 Purpose: To investigate the correlations between random blood glucose, neurological score and prognosis of spontaneous in- tracerebral hemorrhage (SICH).

Methods: A total of 128 SICH patients were recruited over a 1-year period for this study and randomly assigned to two groups: control group (49 patients with random blood glucose level<6.1 mmol/L) and observation group (79 patients with random blood glu- cose level≥6.1 mmol/L). The observation group consisted of 37 males and 42 females aged 22 to 72 years (mean age= 62.7±11.6 years), while the control group consisted of 26 males and 23 females aged 21 to 67 years (mean age= 58.4±10.9 years). Independent and multiple risk factors influencing SICH in the two groups were analyzed. The correlations between the level of random blood glucose, neurological score and prognosis were also assessed.

Results: Age and National Institutes of Health Stroke Scale (NIHSS) scores were significantly higher in the observation group than in control group, and random blood glucose level after admission was positively correlated with NIHSS scores (r= 0.309, p<0.05). Modified Rankin Scale (mRS) ≤ 2 and ≥ 3 were significantly higher in the observation group than in control group, but mRS ≤ 1 and death were significantly lower in observation group than in control group (p<0.05). The results of Logistic regression analysis showed that age (OR: 1.027, 95% CI: 1.010 - 1.045) and NIHSS scores at admission (OR: 1.547, 95% CI: 1.216 - 1.968) were independent risk factors for poor prognosis of SICH (mRS≥3) (p<0.05).

Conclusion: Spontaneous cerebral hemorrhage, Blood glucose level, Severity, Prognosis, Correlation.