CHANGES OF THE LEVELS OF PCT AND CRP IN URINARY TRACT INFECTION OF ELDER PATIENTS AND THEIR CLINICAL SIGNIFICANCE

XIAO-YING GAO¹, MING XI², YAN-BING CHEN³, GUANG-DA XIN

¹Department of Nephrology, Tangshan Gongren Hospital, Tangshan, Hebei, P.R.China, 063000 - ²Department of Urology, Huadu

District People’s Hospital, Southern Medical University, Guangzhou, Guangdong P.R. China, 510800 - 3Department of Nephrology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, P.R.China, 330100

Objective: To analyze the changes of procalcitonin (PCT) and C-reactive protein (CRP) levels in urinary tract infection of elder patients and its clinical significance.

Methods: Randomly, we selected a total of 68 elder patients with urinary tract infection. 32 patients with upper urinary tract infection were enrolled into the Group I, 36 with lower urinary tract infection into the Group II, and 30 healthy subjects who attended the physical examinations into the control group. White blood cell count of blood and urine, PCT and CRP were deter- mined for all patients, and comparison of the levels of PCT and CRP before and after treatment and the correlation analysis between the levels of PCT and CRP were carried out for patients in the observation group.

Results: In two observation groups, white blood cell counts of blood and urine and levels of PCT and CRP were higher than those in the control group, while the levels of PCT and CRP in Group I were higher than those in Group II (p<0.05); after active treatment, significant decreases were identified in levels of PCT and CRP in observation groups (p<0.05); Pearson correlation analysis showed positive correlation between PCT and CRP (r=0.73, p<0.01).

Conclusion: Levels of PCT and CRP are sensitive indicators for diagnosis and auxiliary diagnosis of urinary tract infection of elder patients, and conduces to guiding the clinical medication, which are worthy being promoted in clinical practice.