THE CLINICAL EFFECT AND SAFETY ANALYSIS OF DEZOCINE COMBINED WITH LOW CONCENTRATION ROPIVACAINE IN UPPER LIMB SURGERIES

JIE LI, GUOZHEN LI, XIAOZHENG LI, LI YUAN

Department of Anesthesiology, Shanxian Central Hospital, Shanxian 274300, China - *Department of Anesthesiology, The affiliated hospital of Qingdao university, Qingdao 266000, China

Objective: To research the clinical effect of Dezocine combined with low concentration Ropivacaine in upper limb surgeries, and analyze its safety.

Method: 240 patients who had upper limb surgeries were randomly divided into two groups, research group and control group. Each group had 120 patients. Patients in control group were treated with low concentration Ropivacaine. Patients in research group were treated with low concentration Ropivacaine combined with Dezocine. Difference analysis of the two groups was conduc- ted with anesthesia effect, VAS grading, and adverse reactions.

Results: The acting time of anesthesia in research group was significantly shorter than that in control group. The difference had statistical significance (P<0.05). Sensory block and analgesic time in research group were significantly longer than that in con- trol group, and the difference had statistical significance (P<0.05). VAS grading of research group 2h, 4h, 8h after the operation was significantly lower than that in control group, and the difference had statistical significance (P<0.05). The adverse reaction rate in research group (0.83%) was significantly lower than that in control group (13.33%), and the difference had a statistical significan- ce (P<0.05). In addition, patients in both groups did not have retention of urine, skin itch, respiratory depression, or any other seve- re adverse reaction.

Conclusion: mixed solution of Dezocine and low concentration Ropivacaine had a quick anesthetic effect, long anesthesia and analgesic time, low adverse reaction rate and high clinic safety.