* Associate Professor in Biotechnology, Department of Biotechnology, Qazvin University of Medical Sciences, Qazvin, Iran - **Associate Professor in Periodontics and Dental Caries Prevention Research center, College of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran - ***Dentist, Associate Professor in Periodontics and Dental Caries Prevention Research Center, Qazvin University of Medical Sciences, Shaheid Bahonar Blvd, Qazvin, Iran


Background and aim: Chewing gums have been suggested as an adjunctive method to improve the oral hygiene recently. In addition; due to the anti-inflammatory and anti-bacterial properties of the propolis; its positive properties can be combined with the chewing gum’s characteristics when using propolis as a component of chewing gum in order to improve the oral hygiene indices. This study evaluated the effects of biologic chewing gum enriched by propolis on the clinical periodontal indices.

Materials an methods: In this double-blind clinical trial; 20 eligible volunteers were selected and used Propolis-contained or propolis-free chewing gums (5 sticks daily for 20 minutes after main meals) for 3 days with two weeks wash-out time. In the third period; the participants did not used any chewing gum. They were asked not to use other chewing gums or other oral hygiene habits in the study periods. The routine oral hygiene habits were followed in the wash-out period. Plaque (4) and gingival (7) indices were measured before and after using chewing gums and the data were subjected to one-way analysis of variance in the 3 groups. The paired comparisons were done by Schaeffer test.

Results: Following the consumption of propolis gum, the mean total gingival indices (13/0); gingival index of lingual surface of the teeth (07/0); buccal surfaces of the teeth (19/0); maxilla (11/0); mandible (16/0), was reduced (0001 / 0p <) compared to values seen before taking the gum, while the values of the two groups; one consuming no gum and the other using propolis-free gum, increased. On the other hand, the increase in plaque index in the period without gum was significantly more than the periods of chewing gum containing proposes and proposes-free gum but the difference between the two types of chewing gum were not significant.

Conclusion: Together with the positive effects of the proposes-contained chewing gum in the improvement of gingival index and its ability to prevent an increase in plaques; the gum can be used as an adjunctive method to improve oral hygiene level in the eligible individuals.


Gum based delivery, Periodontal indices, Proposes, Chewing gum, Gingival index, Plaque index.