CASE STUDY OF CHORIOCARCINOMA FOLLOWING A TERM PREGNANCY

MAASOUMEH MIRZAMORADI¹, MAASOUMEH SALEH²*, PARICHEHR KIMIAEE³

¹ Assistant professor of perinatology, Mahdiyeh Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran - ² Department of gynecology and obstetrics, Shahid Beheshti University of Medical Sciences, Tehran, Iran - ³ Assistant professor of oncology, Mahdiyeh Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Choriocarcinoma is the most aggressive form of gestational trophoblastic disease.Post-partum choriocarcinoma is an infrequent event with poor prognosis. A 25 years-old woman presented with vaginal bleeding and then hemoptysis after a term delivery. Laboratory evaluation showed serum B-HCG level:13,420mIU/ml and chest x-ray showed multiple metastases to the lung. Biopsy report of curettage showed choriocarcinoma. After diagnosis, Etoposide, Methotrexate, Dactinomycin, Cyclophosphamide & Vincristine (EMACO) therapy was started. At present, the patient has been 3 serial negative B-HCG levels.