Authors
LUTFI DOGAN*, MEHMET ALI GULCELIK*, NIYAZI KARAMAN*, EMEL BASKAN*, YAVUZ SELIM KAHRAMAN*, BULENT
AKSEL*, CIHANGIR OZASLAN*
Departments
*Department of General Surgery, Ankara Oncology Training and Research Hospital, Ankara, Turkey
Abstract
Aims: Atypical cytologies were categorized as Bethesda category III (atipia with unknown significance, follicular lesions with
unknown significance, AUS/ FLUS) and Bethesda category IV (follicular neoplasm or suspicious for follicular neoplasm, FN/SFN) in
Bethesda system for reporting thyroid cytopathology (BSRTC). This study was planned to define the contribution of clinical and radiological
features in the course of action for AUS/FLUS and FN/SFN thyroid nodules.
Materials and methods: The age, gender, nodule size and definitive pathological results of 124 patients treated with total thyroidectomy
after preoperative diagnosis of AUS/FLUS and FN/SFN lesions were recorded. Radiological features were grouped as increased
vascularity, irregular borders, microcalcification, cystic component, presence of hypoechoic halo, hypoechogenicity and extraglandular
involvement.
Results: The malignancy rates in AUS/FLUS and FN/SFN lesions were 8% and 16.3%, respectively. Fine needle aspiration
cytology (FNAC) was repeated only in 8 patients among 75 patients diagnosed as AUS/FLUS, but the diagnosis was not changed in
direction to follow-up. The presence of irregular borders at ultrasonography, increased vascularity, microcalcification, presence of
hypoechoic halo and hypoechoic nodules were found to be related to the malignancy in AUS/FLUS group. On the other hand, age less
than 50, presence of irregular borders, increased vascularity and presence of microcalcifications were found to be related to the malignancy
in FN/SFN group.
Conclusions: The success of BSRTC in prevention of unnecessary thyroidectomies shows differences between clinics.
Radiological criteria apart from patient’s related factors play an important role in clinical judgement. Microcalcifications seem to be
the most sensitive criteria both in AUS/FLUS and FN/SFN lesions. Irregular border was the criteria with the highest specificity in both
categories.
Keywords
Bethesda, Fine needle, Thyroid, Ultrasound
DOI:
10.19193/0393-6384_2016_1_23