Authors
INCI A1
, DEMIRARAN Y2
, ERUS S3
, OCAK T4
, YAPRAK U3
, AKMAN C4
, BASTURK M4
, KALAFAT UM4
Departments
1
Kanuni Sultan Suleyman Training and Research Hospital, Department of Infectious Disease and Clinical Microbiology, Istanbul -
2
Kanuni Sultan Suleyman Training and Research Hospital, Department of Anesthesiology and Intensive Care, Istanbul ,- 3
Koc
University Faculty of Medicine, Department of Thoracic Surgery, Istanbul - 4
Kanuni Sultan Suleyman Training and Research
Hospital, Department of Emergency Medicine, Istanbul, Turkey
Abstract
Introduction: Intensive care unit (ICU) hospital infections are a global problem concerning the whole world. Sensitivity and
specificity of parameters such as CRP (C-reactive protein), erythrocyte sedimentation rate and WBC (white blood cell), which are
among the classical markers of systemic inflammation, were reported to have limited benefit in patients with these types of bacterial
infections. PCT (procalcitonin) has been a focus of interest as a specific and early marker in systemic inflammation, sepsis and infections
especially in recent years. In this study, we aimed to evaluate potential usability of PCT in distinction of systemic and localized
bacterial infections in patients who are followed up in ICU and to compare CRP, WBC and MPV (mean platelet volume) values in
patients with systemic and localized bacterial infections.
Materials and methods: Totally 52 patients who were followed in Adult ICU of our hospital were included in the study. The
patients were divided into two groups. Group 1 consisted of patients with growth in blood culture and systemic bacterial infection clinic.
Group 2 consisted of patients with growth in phlegm, tracheal aspirate, wound and urine culture without growth in blood culture.
Age, gender, growth region and growing microorganisms, simultaneously checked CRP, PCT, WBC, MPV values were recorded in follow-up
form.
Results: The study showed that PCT value was significantly high in systemic infections, while other parameters did not show a
significant difference between the two groups. Furthermore, Acinetobacter baumannii was found to be the most common agent.
Conclusion: Our study suggests that PCT value has a more valuable potential than other standard infection parameters in
distinction of systemic infection and localized bacterial infection in patients who are followed in ICU. However, we believe that more
comprehensive studies with a larger sampling can guide the clinicians for early diagnosis and treatment.
Keywords
Intensive care unit, mean platelet volume, procalcitonin, crp
DOI:
10.19193/0393-6384_2016_1_39