JUN LI1,2,3,4,5, CHANGBIN LIU1,2,3,4,5, CHONG WANG1,2,3,4,5, LIANGJIE DU1,2,3,4,5, XUECHAO DONG1,2,3,4,5, YUN GUO1,2,3,4,5, FENG GAO1,2,3,4,5, HONGWEI LIU1,2,3,4,5, LIANG CHEN1,2,3,4,5, JIANJUN LI1,2,3,4,5
1School of Rehabilitation Medicine, Capital Medical University - 2Department of Spinal and Neural Function Reconstruction, Beijing Bo’ai Hospital China Rehabilitation Research Center - 3Institute of Rehabilitation Sciences of China, China Rehabilitation Research Center - 4Center of Neural Injury and Repair, Beijing Institute for Brain Disorders - 5Beijing Key Laboratory of Neural Injury and Rehabilitation
Objective: To clarify the effect of transferring lateral head of gastrocnemius muscle on the treatment of deep peroneal nerve injuries in rats.
Methods: Thirty-two rats were randomly divided into sham group, control group with injury of the deep peroneal nerve, the neural anastomosis group and the nerve transfer group. We measured walking tracks analysis, electrophysiology, wet weight and cre- atine phosphokinase of anterior tibial muscle, and the branching pattern, length, diameter of motor branches of the tibial nerve in the proximal leg, the maximum dissected length of the common fibular nerve to the proximal and the diameter of deep fibular nerve.
Results: After the intra-neural dissection of the common fibular nerve, the lateral head of gastrocnemius muscle was long enough for direct nerve suture with the deep fibular division without tension. After 12w of surgery, peroneal nerve function index, compound muscle action potential, wet weight and creatine phosphokinase of anterior tibial muscle in the nerve transfer group were higher than them in the control group, but there was no significant difference of them when compare with the neural anastomosis group.
Conclusion: Transferring lateral head of gastrocnemius muscle for treatment of deep peroneal nerve injuries in rats is effective.
gastrocnemius muscle, peronal nerve injure, nerve transposition operation, reconstruction