YASEMIN ARDIÇOĞLU AKIŞIN1, ZEYNEP NUR KARAGÖZ2, MUSTAFA TURAN3, NEJAT AKAR4
1Biochemistry, TOBB ETU Faculty of Medicine, Ankara, Turkey - 24th Year Student, TOBB ETU Faculty of Medicine, Ankara, Turkey - 3Department of Medical Education, TOBB ETU Faculty of Medicine, Ankara, Turkey - 4Department of Pediatrics, TOBB ETU Faculty of Medicine, Ankara, Turkey
Introduction: We investigated the use of Platelet-to-Lymphocyte Ratio (PLR) which can be calculated by using platelet and lymphocyte counts from total blood count, for the diagnosis of infectious mononucleosis (IM).
Materials and methods: Out of 116 patients, 24 of them were diagnosed as IM with regard to serological tests and accepted as patient group. 40 healthy subjects were taken as control group. PLR values of the patient and control groups were calculated and cutoff values were determined using ROC Curve analysis.
Results: According to the study data, sensitivity and specificity of PLR value in diagnosing IM is 50% and 95%, respectively.
Conclusion: We concluded that low values of PLR can be used to give an idea about the existence of IM. However, high values of PLR may necessitate more evaluation for other differential diagnosis.
Infectious Mononucleosis, Epstein-Barr Virus, Platelet, Lymphocyte