FARZAD AHMADABADI1, MANOUCHEHR BARAK2, AFSHIN MASHAYEKHI3, MAHNAZ ZAREAKBARI4*, NARJES JAFARI5, NAHID NAJAFI6
1Pediatric Neurologist, Ardabil University of Medical Sciences, Ardabil, Iran - 2Pediatric Infectious disease specialist, Ardabil University of medical science, Ardabil, Iran - 3Neurologist, University of Istanbul, Istanbul, Turkey - 4Pediatrician, Ardabil University of Medical Science, Ardabil, Iran - 5Pediatric Neurologist, Shahid Beheshti University of Medical Science, Tehran, Iran - 6Pediatrician, Tehran University of Medical Science, Tehran, Iran
Objectives: Behavioral problems are considered as the side effects of phenobarbital consumption in children. Thus, the aim of this research is studying the effect of vitamin B6 on behavioral disorders due to use of phenobarbital in patients with seizure.
Patients and methods: In this study, 77 patients (Children with Seizures) were studied and divided to needs to be removed two groups. Phenobarbital along with vitamin B6, and phenobarbital along with a placebo were separately prescribed to the two groups for three months, and behavioral changes were recorded and the data were collected and provided for the statistical software.
Results: In the first three months, no significant difference was observed between the two groups, and in the second three months, the average value of hyperactivity behavior removed significantly decreased. In the drug group in the first three months and placebo group in the second three months, hyperactivity and aggressive behaviors significantly reduced moreover, With respect to all three behaviors, the placebo group in the first three months and drug group in the second three months the Were not significantly dif- ferent.
Conclusion: vitamin B6 can be effective in the reduction of hyperactivity behavior in the children.
vitamin B6, phenobarbital, behavioral disorders, seizures