VIRGINIE LAVOIPIERRE1,2, JAD KERBAJ1,2, MATTHIEU MILLION1,2,3, PHILIPPE BROUQUI1,2,3
1Assistance Publique Hôpitaux de Marseille, CHU Nord, Pôle Maladies Infectieuses, Service de Maladies Infectieuses, Institut Hospitalo-Universitaire Méditerranée Infection, 13015 Marseille, France -2Aix Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, 13005 Marseille, France - 3Institut Hospitalo-Universitaire Méditerranée Infection, 13005 Marseille, France
Introduction: Yersinia enterocolitica is a frequent bacterial cause of gastroenteritis. Extra-intestinal complications are uncom- mon. We report a case of Yersinia enterocolitica hepatic miliary, leading to diabetes mellitus diagnosis.
Case presentation: A 36-year-old patient with medical history of untreated mild chronic ulcerative colitis was admitted for persisting fever, pharyngitis and headache without abdominal symptom. Blood tests showed inflammatory syndrome, mild cytolysis and multiple hepatic micro-abscesses were found on abdominal computed tomography. Blood culture returned positive for Yersinia enterocolitica. Patient received five days of intravenous ceftriaxone and gentamicin, then ciprofloxacin for six weeks with good clini- cal and biological outcome. Patient was also diagnosed with type 2 diabetes. As ferritin level was high, we looked for mutation of HFE gene: patient had heterozygous H63D mutation.
Conclusion: This case report aims at showing an unusual manifestation of Yersinia enterocolitica infection and underlines the importance of type 2 diabetes rather than iron overload as underlying condition.
Yersinia enterocolitica, hepatic abscesses, hepatic miliary, HFE, diabetes mellitus