NAHID SALEHI1, MOHAMMADREZA SAIDI1, ALIREZA RAI1, SIMIN MOHEGHI1, HOOMAN TADBIRI2*
Cardiovascular research center, Kermanshah University of Medical Sciences, Kermanshah, Iran -
Iran University of Medical Sciences, Tehran, Iran
Background: The co-occurrence of pulmonary artery hypertension and heart diastolic dysfunction can increase the chance of
death. We aimed to compare the right ventricular (RV) diastolic function in pulmonary artery hypertensive patients and healthy individuals
using the echocardiography findings.
Methods: In this study, 32 individuals with pulmonary artery pressure of ≥40 were selected as a case group and 32 healthy
individuals were selected as the control group, and the echocardiography indices of RV diastolic function were compared between the
Results: Nineteen individuals in the case group had RV diastolic dysfunction (59.4%), while none were observed in the control
group (p<0.001). The mean (±SD) of E/E' ratio was significantly higher in the case group compared to the control group, which confirms
the RV dysfunction (P= 0.002). Although the tricuspid peak A velocity in the case group was significantly higher compared to
the control group, its rate was within the normal range in both groups (P= 0.01). In addition, the mean (±SD) of the E/A ratio and
E'/A' ratio were significantly lower in the case group than in the control group, which showed the RV dysfunction (p < 0.05). There
were no significant differences in the other RV diastolic indices between the two groups (p>0.05).
Conclusions: The presence of pulmonary hypertension can affect the RV diastolic indices, and this is explained in our study by
the decreased E/A ratio. Therefore, considering the role of RV diastolic function in the prevention of heart failure and its complications,
understanding the current status of these indices is highly important.
pulmonary arterial hypertension; diastolic function; right ventricle; echocardiography.