1 Cardiovascular research center, Kermanshah University of Medical Sciences, Kermanshah, Iran - 2 Iran University of Medical Sciences, Tehran, Iran


Background: The co-occurrence of pulmonary artery hypertension and heart diastolic dysfunction can increase the chance of death. We aimed to compare the right ventricular (RV) diastolic function in pulmonary artery hypertensive patients and healthy individuals using the echocardiography findings.

Methods: In this study, 32 individuals with pulmonary artery pressure of ≥40 were selected as a case group and 32 healthy individuals were selected as the control group, and the echocardiography indices of RV diastolic function were compared between the two groups.

Results: Nineteen individuals in the case group had RV diastolic dysfunction (59.4%), while none were observed in the control group (p<0.001). The mean (±SD) of E/E' ratio was significantly higher in the case group compared to the control group, which confirms the RV dysfunction (P= 0.002). Although the tricuspid peak A velocity in the case group was significantly higher compared to the control group, its rate was within the normal range in both groups (P= 0.01). In addition, the mean (±SD) of the E/A ratio and E'/A' ratio were significantly lower in the case group than in the control group, which showed the RV dysfunction (p < 0.05). There were no significant differences in the other RV diastolic indices between the two groups (p>0.05).

Conclusions: The presence of pulmonary hypertension can affect the RV diastolic indices, and this is explained in our study by the decreased E/A ratio. Therefore, considering the role of RV diastolic function in the prevention of heart failure and its complications, understanding the current status of these indices is highly important.


pulmonary arterial hypertension; diastolic function; right ventricle; echocardiography.