NAHID SALEHI1, HOSSEIN AZAM2, MOSTAFA BAHREMAND1*
Cardiology Department, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran
Kermanshah University of Medical Sciences, Kermanshah, Iran
Neutrophil-to-lymphocyte ratio (NLR) has been noted recently as a prognostic factor in patients with cardiovascular diseases.
The present study was done to find any relationship between NLR and number of diseased coronary arteries in patients underwent
coronary angiography in Imam Ali University Hospital of Kermanshah, Iran between 2012 and 2014.In this retrospective study,
medical records of 1,498 patients who underwent coronary angiography were reviewed. The data extracted were entered into a
checklist. NLR was calculated using complete blood count (CBC) reports and the number of diseased coronary arteries was determined
using coronary angiography reports. The data were analyzed using SPSS software (ver. 20.0) by analysis of variance (ANOVA), t
test, Kruskal-Wallis, and Pearson correlation tests.There were significant (P< 0.05) relationships between NLR, history of cardiovascular
diseases, diabetes mellitus, hypertension, left ventricular ejection fraction (LVEF), fasting blood sugar, serum creatinine and
urea, white blood cell (WBC) count, hemoglobin, platelet count, MCV (mean corpuscular volume), and with the number of diseased
coronary arteries detected on coronary angiography. However, there was no significant relationship (P> 0.05) between history of
hyperlipidemia, cigarette smoking, alcohol drinking, type of cardiac chest pain (acute or chronic), serum total cholesterol, HDL
(high-density lipoprotein), LDL (low-density lipoprotein), and triglyceride with the number of diseased coronary arteries. NLR was
effective on the number of diseased coronary arteries (i.e., the severity of disease). Application of this laboratory factor can be helpful
in patients with ischemic heart disease.
Neutrophil-to-lymphocyte ratio (NLR); coronary artery disease; angiography.